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Reduced appetite and improved metabolic function often contribute to steady weight reduction over time

Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): Prospective observational study

Review proposal of semaglutide for managing overweight and obesity (TA1152 review proposal) BMI threshold adjustments

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Key ways it appears to mimic or amplify natural gastrointestinal and tissue repair mechanisms observed in animal studies: Strongly upregulates angiogenesis through multiple pathways (VEGF, EGR-1, FAK-paxillin) in injured tissues, similar to the bodys own response during normal wound healing and tendon/ligament repair